What It's For & How To Take
Ledipasvir/sofosbuvir is a combination of 2 antiviral medications that are used to treat chronic hepatitis C. These two medications work together to decrease the amount of hepatitis C virus in the body while also stopping the virus that causes hepatitis C from spreading in the body.
Hepatitis means inflammation of the liver. Toxins, certain drugs, some diseases, heavy alcohol use, and bacterial and viral infections can all cause hepatitis. Hepatitis is also the name of a family of viral infections that affect the liver. The most common types are Hepatitis A, Hepatitis B, and Hepatitis C.
Hepatitis C is a contagious liver disease that ranges in severity from a mild illness lasting a few weeks to a serious, lifelong illness that attacks the liver. The Hepatitis C virus is spread primarily through contact with the blood of an infected person.
Ledipasvir/sofosbuvir may treat hepatitis C in the person it is prescribed for, it is not known if this medication will prevent the spread of hepatitis C to other people.
Ledipasvir/sofosbuvir is available as a tablet and is usually ordered to be taken once daily, with or without food. This medication works best when a constant level is maintained in your body. Take your dose at the same time each day.
If you are taking antacids containing aluminum or magnesium, such as MaaloxTM or MylantaTM, take them at least 4 hours before or after your dose of ledipasvir/sofosbuvir. The antacid may decrease the absorption of this medication, and it may not work as well.
If you miss a dose, take it as soon as you remember. If it is near the time of your next dose, skip it and continue with your normal dose time. Do not take a double dose to make up the missed dose.
The length of your treatment will be anywhere between 8 – 24 weeks. Your duration of treatment will depend on your condition, response to treatment, and severity of side effects. Do not stop taking your medication without talking to your doctor first.
This medication is sometimes used to treat other conditions. Talk with your doctor of pharmacist if you are prescribed this medication to treat something that is not listed here.
Most Important Warnings
- Current or previous Hepatitis B infections may be re-activated when Hepatitis C infections are treated with this medication. Rarely, this may lead to liver failure or death.
- Patients treated for Hepatitis C should be screened for evidence of Hepatitis B before, during and after treatment with this medication.
Warnings & Cautions
- When this medication is taken with heart rhythm medications, some patients have developed a slow heartbeat. Call your doctor right away if you develop symptoms of a slow heartbeat such as dizziness or lightheadedness.
- Currently, there is inadequate literature to assess the risk or safety of using this medication in women who are pregnant or breastfeeding. If you are taking this medication and think you may be pregnant, contact your doctor immediately.
- This medication may make you dizzy, drowsy, or blur your vision. Do not drive or do any activity that requires focus and attention until you are sure you can do them Avoid alcoholic beverages while taking this medication.
Interactions & Side Effects
- Tell your pharmacist or doctor all your medication allergies so they may determine if ledipasvir/sofosbuvir is safe for you to take.
- Avoid dangerous drug interactions. Medications that affect liver metabolism may significantly change how well this medication works. Tell your pharmacist or doctor all the other medication you are taking, including over the counter supplements, even if you don't take them very often.
- Ask your doctor if this medication is safe to take with your current health conditions. Tell your doctor if you have any kidney disease, heart disease, immune system problems or any other type of liver disease.
- While taking this medication, you may feel some tiredness, headache, sleep disorders, a slight cough, and perhaps some nausea or diarrhea. If these or any other unwanted side effects persist, contact your doctor or pharmacist to talk about it with them.
- Call your doctor right away if you have any excessive tiredness, confusion or memory problems, fainting, slow heartbeat, or a skin rash that may happen with blisters and swelling.
- Call emergency 911 if you have any symptoms of a heart attack such as chest and left arm pain, shortness of breath and sweating or if you have symptoms of a stroke such as weakness on one side of your body, slurred speech, sudden vision changes, and confusion.